pCEST: Positive contrast using Chemical Exchange Saturation Transfer
نویسندگان
چکیده
منابع مشابه
pCEST: Positive contrast using Chemical Exchange Saturation Transfer.
Chemical Exchange Saturation Transfer (CEST) contrast utilizes selective pre-saturation of a small pool of exchanging protons and subsequent detection of the decrease in bulk water signal. The CEST contrast is negative and requires detection of small signal change in the presence of a strong background signal. Here we develop a Positive CEST (pCEST) detection scheme utilizing the analogous natu...
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Chemical exchange saturation transfer (CEST) imaging is sensitive to dilute labile proton and microenvironment properties such as pH and temperature, and provides vital information complementary to the conventional MRI methods. Whereas the Bloch equations coupled by exchange terms (i.e., Bloch-McConnell equations) have been utilized to quantify 2-pool CEST contrast, it is tedious to extend the ...
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ژورنال
عنوان ژورنال: Journal of Magnetic Resonance
سال: 2012
ISSN: 1090-7807
DOI: 10.1016/j.jmr.2011.12.011